Does alcohol affect the effectiveness of ART

 
Most anti retrovirals (ART) have _no interaction_ with alcohol. It is usually safe to consume alcohol even if you are taking ART. Alcohol can however make the side effects of some drugs (Efavirenz for example) worse. For the large part, moderate drinking of alcohol will not affect your ART. It is always best to consult with your doctor about the interactions of alcohol and the specific drugs that you are taking. The larger problem with alcohol is that individuals are prone to miss their dosage of ART. You say that you never miss a dose, but alcohol intake is associated with decreased adherence to ART programs. High alcohol intake is also associated with other high risk behaviour, for example drug abuse and unsafe sexual behaviour.